Unique high-through-put extraction procedure for Neurotransmitters
This latest technology (sample clean-up device) provides a solution for the extraction of neurotransmitters/biomolecules from biological fluids wherein an ion exchange resin is attached to a solid support such as a multiwell plate (patent pending):
Advantages:
- Much more cost-effective than chromatography columns
- Fast and easy to use
- Suitable for biomolecules in different kinds of biological fluids
- Improved sensitivity/small sample volumes
- Applicable in high throughput procedures
GABA concentrations measured by a new ELISA in different regions of rat neuronal tissue:
| Tissue sample | Measured conc.(pmol/mg wet weight tissue) |
| Motor Cortex | 1137 ± 65 |
| Somatosensory cortex | 1379 ± 115 |
| Hippocampus | 1719 ± 219 |
| Cervical sc region | 484± 65 |
| Thoracic sc region | 395 ± 19 |
| Lumbar I & II sc region | 540 ± 80 |
| Lumbar III – VI sc region | 737 ± 32 |
| Sacral sc region | 687 ± 48 |